【Product Name】High Purity Benfotiamine powder
Description Of Benfotiamine
Benfotiamine (rINN, or S-benzoylthiamine Omonophosphate) is a synthetic Sacyl derivative of thiamine (vitamin B1). It has been licensed for use in Germany since 1993. It is prescribed there for treating sciatica and other painful nerve conditions.
Benfotiamine is marketed as a dietary supplement and is not a medicine. Benfotiamine is primarily marketed as an antioxidant dietary supplement. In a clinical study with six patients, benfotiamine lowered
AGE by 40%.
Benfotiamine may be useful for the treatment of diabetic retinopathy, neuropathy, and nephropathy.
However, most of the effects attributed to benfotiamine are extrapolated from in vitro and animal
studies. Unfortunately, apparent evidences from human studies are scarce and especially endpoint
studies are missing. Therefore, additional clinical studies are mandatory to explore the therapeutic
potential of benfotiamine in both diabetic and non-diabetic pathological conditions. It is thought
that treatment with Benfotiamine leads to increased intracellular thiamine diphosphate levels, a
cofactor of transketolase. This enzyme directs advanced glycation and lipoxidation end products (AGE's,
ALE's) substrates to the pentose phosphate pathway, thus reducing tissue AGEs.
Function & Application
1. Benfotiamine is used for the prevention and treatment of vitamin B1 deficiency;
2. It is used in the treatment of non alcoholic wernicke encephalopathy;
3. To treat beriberi;
4. For vitamin B1 demand increase, with inadequate intake from foods supplies (fatigue, hyperthyroidism, pregnancy, lactation, during strenuous manual labor, etc.
【Storage】Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.