Description Of Benfotiamine
Benfotiamine is vitamin B1 fat soluble derivatives, improve the bioavailability of water-soluble vitamin B1 low shortcomings, improve the blood and tissue concentrations of thiamine, so as to improve the curative effect.
Benfotiamine may be useful for the treatment of diabetic retinopathy, neuropathy, and nephropathy. However, most of the effects attributed to benfotiamine are extrapolated from in vitro and animal studies. Unfortunately, apparent evidences from human studies are scarce and especially endpoint studies are missing. Therefore, additional clinical studies are mandatory to explore the therapeutic potential of benfotiamine in both diabetic and non-diabetic pathological conditions. It is thought that treatment with Benfotiamine leads to increased intracellular thiamine diphosphate levels, a cofactor of transketolase. This enzyme directs advanced glycation and lipoxidation end products (AGE's, ALE's) substrates to the pentose phosphate pathway, thus reducing tissue AGEs.
Function & Application Of Benfotiamine
1. Benfotiamine is used for the prevention and treatment of vitamin B1 deficiency;
2..Benfotiamine is used in the treatment of non alcoholic wernicke encephalopathy;
3. Benfotiamine is used in the following diseases, speculation and vitamin B1 deficiency and metabolic disorders associated with treatment, such as: neuralgia; Muscle pain, joint pain; Peripheral neuritis, peripheral nerve palsy; Myocardial metabolic disorders; Constipation and other gastrointestinal motor function obstacle.
【Storage】Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.